protamine


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Related to protamine: protamine insulin

pro·ta·mine

 (prō′tə-mēn′, -mĭn) also pro·ta·min (-mĭn)
n.
Any of a group of arginine-rich proteins that bind to and package DNA in the sperm nucleus. Protamines are used in long-acting formulations of insulin and to neutralize the anticoagulant effects of heparin.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

protamine

(ˈprəʊtəˌmiːn)
n
(Biochemistry) any of a group of basic simple proteins that occur, in association with nucleic acids, in the sperm of some fish
[C19: from German: see proto-, amine]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

prot•a•mine

(ˈproʊ təˌmin, prɒˈtæm ɪn)

n.
any of a group of arginine-rich, strongly basic proteins that are not coagulated by heat.
[1870–75]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.protamine - a simple protein found in fish sperm; rich in arginine; simpler in composition than globulin or albumin; counteracts the anticoagulant effect of heparin
simple protein - a protein that yields only amino acids when hydrolyzed
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
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References in periodicals archive ?
Scrotal heat stress induces altered sperm chromatin structure associated with a decrease in protamine disulfide bonding in the stallion.
Sperm chromatin integrity: etiologies and mechanisms abnormality, assays clinical importance, preventing and repairing damage
At the termination of CPB, heparin was neutralized with protamine sulfate.
The effects of intra-operative amiodarone loading on the systemic inflammatory response syndrome induced by cardiopulmonary bypass/Kardiyopulmoner baypasin indukledigi sistemik inflamatuvar yanit sendromunda intraoperatif amiodaron yuklemesinin etkisi
When staff realised their mistake, they administered protamine sulphate, a drug that reverses the effects of heparin.
OUAID'S TWINS FIGHT FOR LIFE AFTER HUGE OVERDOSE BLUNDER
These liposomes, dispersed in 10% serum-containing growth medium, efficiently delivered ON precondensed by protamine sulfate (PS) into HeLa cells.
Oligonucleotide delivery with serum into HeLa cells using polycation liposomes
The experts in Dictionary Corner were stunned when he came up with such words as craniates, tzardoms, protamine, valorise and renegado.
Conor, 14, crowned youngest Countdown champion
Novo Nordisk's FlexPen is the leading insulin delivery device in the United States and is used with Novo Nordisk's NovoLog Mix 70/30 (70% insulin aspart protamine suspension and 30% insulin aspart injection, (rDNA origin)), NovoLog (insulin aspart (rDNA origin) injection) and soon-to-be-launched Levemir (insulin detemir (rDNA origin) injection).
Novo Nordisk sues Sanofi-Aventis for insulin delivery device patent infringement
Effect of protamine on the immunological behavior of beta glucuronidase in mice and patients with hay fever.
Enzyme-potentiated desensitization in otolaryngic allergy
Nucleohistone from calf thymus, histone-free protamine from salmon, salmon testis nucleoprotamine and ubiquitin from bovine red cells were also obtained from Sigma.
Thymus-pituitary interactions during ageing
THURSDAY, July 12, 2018 (HealthDay News) -- Initiation of a basal insulin analog versus human neutral protamine Hagedorn (NPH) insulin is not associated with reduction in the risk of hypoglycemia-related emergency department visits or hospital admissions, according to a study published in the July 3 issue of the Journal of the American Medical Association.
Basal Insulin Analogs Don't Cut Hypoglycemia-Linked ER Visits; No reduced risk of hypoglycemia-linked ER visits, admissions for basal insulin analog vs. NPH insulin
Previous studies of testicular biopsy samples on gene expression analyzed the relationship between the Johnsen assessment with the cAMP responsive element modulator (CREM), protamine 1 and protamine 2 genes and emphasized on stages of spermatogenesis, in particular in the sperm packaging.
Decreased Expression of CDC25A in Azoospermia as the Etiology of Spermatogenesis Failure

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