OCRL

(redirected from INPP5F)

OCRL

A gene on chromosome Xq25 that encodes phosphatidylinositol polyphosphate 5-phosphatase, an enzyme involved in actin polymerisation and possibly also in lysosomal membrane trafficking.

Molecular pathology
OCRL mutations cause oculocerebrorenal syndrome of Lowe and Dent disease.

Mentioned in ?

Lowe syndrome
oculocerebrorenal syndrome
OFD1

References in periodicals archive ?

Wang et al., "Gene-silencing screen for mammalian axon regeneration identifies Inpp5f (Sac2) as an endogenous suppressor of repair after spinal cord injury," The Journal of Neuroscience, vol.

AAV-KLF7 Promotes Descending Propriospinal Neuron Axonal Plasticity after Spinal Cord Injury

CITE

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