Radiotherapy devices are expected to remain of great use in treatment of pancreatic cancer and borderline
resectable cancer.
The trial plans to enroll a total of 45 patients with advanced or borderline
resectable pancreatic adenocarcinoma in a three-arm trial.
Two subjects in the treatment group became
resectable following trial completion (both were initially borderline
resectable) and were alive at follow-up 44 and 35 months from diagnosis.
Philogen currently has two products in Phase III development for oncological indications: Daromun is being investigated for the treatment of fully
resectable Stage III B / C melanoma; and Fibromun is being studied in metastatic soft tissue sarcoma.
These results explain that metastatic liver lesions, if
resectable, should be excised as it will completely eliminate the source and, hence, would reduce further spread of the tumour.10,11 However, only 10-20% of the patients with liver metastases are candidates for surgical resection at presentation 12,13 while the rest are ineligible for surgery because of the tumour location, size, number of liver lesions, the residual normal liver and extra-hepatic disease progression.14,15 The current study was planned to identify the risk factors responsible for the development of metastatic lesions in liver after curative surgical resection of the primary rectal carcinoma.
In multivariate Cox regression test, PAI-1 expression was identified as an independent predictor for long-term prognosis of
resectable PDAC (hazard ratio = 2.559, 95% confidence interval = 1.499-4.367, P = 0.001).
However, only 15-20% of patients with pancreas cancer have
resectable disease at the time of admission (2).
M2 PHARMA-November 15, 2018-Brooklyn ImmunoTherapeutics Presents Positive Results of IRX-2 Therapy in
Resectable Breast Cancer and Head and Neck Cancer
A structured approach toward the disease with the aid of clinical, noninterventional/interventional radiology and laparoscopic findings has helped surgeons to choose between an aggressive approach of radical cholecystectomy for those with a
resectable growth and suitable palliation for those who are unlikely to benefit from therapeutic laparotomy, thereby helping in proper and judicious utilization of health-care resources.
Patients with anal margin carcinoma with a lesion smaller than 2 cm had a wide local excision if it was deemed
resectable with preservation of the sphincter.
Patients with a
resectable cardiac hemangioma have good surgical outcome and prognosis.
Bavarian Nordic A/S (CPH:BAVA), a fully integrated biotechnology company, announced on Wednesday that the first patient has been dosed in a phase 2 study evaluating the combination therapy of its cancer vaccine, CV301, and Bristol Myers Squibb's checkpoint inhibitor, nivolumab (OPDIVO), for the treatment of patients with
resectable hepatic-limited metastatic colorectal cancer (mCRC).