intrinsic factor

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Related to intrinsic factor: extrinsic factor, pernicious anemia, Intrinsic pathway

intrinsic factor

A glycoprotein that is secreted by the gastric mucous membrane and is essential for the absorption of vitamin B₁₂ in the intestines.

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

intrinsic factor

(Biochemistry) biochem a glycoprotein, secreted by the stomach, the presence of which is necessary for the absorption of cyanocobalamin (vitamin B12) in the intestine

Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

intrin′sic fac`tor

a gastric glycoprotein involved in the absorption of vitamin B₁₂.

[1925–30]

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Noun

intrinsic factor - a substance produced by the mucosa of the stomach and intestines that is essential for the absorption of vitamin B12; "lack of intrinsic factor can result in pernicious anemia"

factor - anything that contributes causally to a result; "a number of factors determined the outcome"

Translations

in·trin·sic fac·tor

n. factor intrínseco, proteína normalmente presente en el jugo gástrico humano.

English-Spanish Medical Dictionary © Farlex 2012

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References in periodicals archive ?

Laboratory test Time of Three months 24 months presentation before before B12 levels (211-946 pg/mL) 94 631.5 pg/ml 751 pg/ml WCC (4.5-11 x 103/uL) 2.5 4.67 4.5 Hb (12-16 g/dL) 6 11.7 11.1 Platelet (140-440 thou/cumm) 7 142 143 Intrinsic factor antibody 11.9 (0-1.1 AU/mL) Monoclonal spike 3.13 1.07 0.4 (0.7-1.60 g/dL) Table 2: Complete blood count on admission and prior to discharge.

Rapid Onset of B12 Deficiency in the Setting of Worsening Multiple Myeloma: Correlations between B12 Deficiency and Multiple Myeloma

Dental erosion with intrinsic factors predominantly affects the palatal surfaces of maxillary anterior teeth with intact cervical enamel rim [19].

Restorative Rehabilitation of a Patient with Dental Erosion

Questionnaire items were worded using language for instrument development based on Deci and Ryan's (1985) extrinsic and intrinsic factors of self-determination motivation and Bandura's (1997) self-efficacy motivation.

Development and validation of an instrument to assess youth motivation to participate in career development events

The test currently used to identify any Intrinsic Factor Antibodies is the Competitive Binding Luminescence Assay and it's woefully inadequate to the extent that the new Guidelines suggest that if the test for the IF antibody is positive then the patient will have Pernicious Anaemia; however, if the test is negative for the antibody and the patient has the symptoms of the disease then he or she should be diagnosed as having Negative Intrinsic Factor Antibody Pernicious Anaemia.

Pernicious Anaemia, Vitamin B12 deficiency and the podiatrist

Malabsorption, gastric atrophy, and reduced production of "intrinsic factor" are some other causes of deficiency.

Clinical profile and response in patients with megaloblastic anemia

Table 4 shows the mean and the standard deviation of each the main of motivational factors that trigger entrepreneurs in Egypt with highest mean for "For my own satisfaction and growth" Intrinsic Factor with value 4.28 followed by "To be able to use my past experience and training" and "To prove I can do it," Intrinsic Factors with values 4.14 and 4.13, respectively, while the least mean value was 2.98 for "To provide jobs to family members," Family Security factor.

What Are the Triggering Motives for Entrepreneurs in Egypt? A Case Study of Business Administration Post Graduates Students in Egypt

Oral treatment of pernicious anemia with high doses of vitamin B12 without intrinsic factor. Acta Med Scand.

Nutrition hotline

For decades, it has been taught that vitamin [B.sub.12] deficiency in patients with pernicious anemia is due to poor [B.sub.12] absorption caused by a lack of intrinsic factor, and that replacement must be given intramuscularly.

Myth of the month: oral vitamin [B.sub.12] replacement

It causes reversible megaloblastic anemia and the most frequent cause of severe vitamin B12 deficiency is the loss of the intrinsic factor in autoimmune atrophic gastritis.

False increased vitamin B12 levels in autoimmune gastritis and subacute combined degeneration of the spinal cord

Complete blood count differential count folic acid vitamin B12 intrinsic factor gastric parietal cell antibodies and holotranscobalamin II were assessed.

Pernicious anemia in patients with macrocytic anemia and low serum B12

Antibodies to intrinsic factor (AIFA), which block the binding of cobalamin to intrinsic factor, have been reported in 31-76% of patients with pernicious anemia.

Association between vitamin B12 level and anti-parietal cells and anti-intrinsic factor antibodies among adult Jordanian patients with Helicobacter pylori infection

A Pernicious Anaemia test is a simple finger prick blood spot test that can accurately check for the antibodies that bind with Intrinsic Factor (IF).