[6] whole blood was implicated in anaphylaxis (31.7%), FNHTR (14%), transfusion-associated circulatory overload (3.84%), and
TRALI (10%).
US blood centers sometimes exclude women with a history of pregnancy from donation of blood products like platelets or plasma, due to a condition called transfusion-related acute lung injury (
TRALI), Katz said.
Abbreviations HLA - human leucocyte antigens MHC - major histocompatibility complex WHO - World Health Organization CDC - complement dependent cytotoxicity PCR - polymerase chain reaction
TRALI - transfusion related acute lung injury vCJD - variant Creutzfeldt-Jakob disease History
A study reported 7% adverse transfusion reactions, including one due to transfusion-related acute lung injury (
TRALI).4
In an attempt to reduce infectious complications, the use of leukocyte-depleted PRBCs is recommended; in contrast, the pooled solvent-detergent FFP may be preferred over standard FFP to reduce the risk for transfusion-related acute lung injury (
TRALI).
Four had rigors, two had extravascular haemolysis and one had
TRALI (Transfusion-Related Acute Lung Injury) during transfusion that recovered within 24 hours.
Trali, "Learning styles-understanding for learning strategies," Pakistan Armed Forces Medical Journal, vol.
As the patient did not require blood transfusions,
TRALI as cause of ARDS can be ruled out.
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Besides incompatible blood transfusion leading to the hemolytic transfusion reaction, other transfusion reactions occurring in the recipients of blood transfusion are febrile reactions, allergic and anaphylactic reactions, circulatory overload, rarely immunologic complications, and transfusion-related acute lung injury (
TRALI).