Marfan syndrome


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Mar·fan syndrome

 (mär′făn)
n.
A genetic disorder principally affecting the connective tissues of the body, manifested in varying degrees by excessive bone elongation and joint flexibility and by abnormalities of the eye and cardiovascular system.
[After Antonin Bernard Jean Marfan (1858-1942), French pediatrician.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

Marfan syndrome

(ˈmɑːfæn)
n
(Pathology) a disorder of connective tissue that is characterized by abnormal elongation of the bones and often by visual impairment
[C19: named after Antoine Marfan (1858–1942), French paediatrician]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

Mar′fan syn`drome

(ˈmɑr fæn, mɑrˈfæn)

n.
a hereditary disorder characterized by abnormally elongated bones, hypermotility of the joints, and circulatory and eye abnormalities.
[after Antonin Bernard Marfan (1858–1942), French pediatrician, who described it in 1892]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
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References in periodicals archive ?
After the inquest, Ms Mufford called for improved care for people diagnosed with Marfan syndrome.
Boy, 15, died after being sent home with painkillers for severe chest pains; Euan Ellis was a known sufferer of a heart condition called Marfan syndrome - a genetic and sometimes fatal disorder - but despite this had not had a heart scan in four years
The gene defect in Marfan syndrome leads to abnormal production of a protein called fibrillin, resulting in parts of the body being able to stretch abnormally when placed under any kind of stress.
Daughters' rare condition leads to A&E blank looks; People with rare conditions often voice frustrations at having to repeat their symptoms to medics time and time again. Here, one mums speaks how her daughters' 'silent killer'condition is often faced with baffled expressions by hospital staff..
Around one in 5,000 people has Marfan syndrome: those who carry the gene have a 50% chance of passing it on.
People don't realise just how poorly the girls are; MUM TELLS OF BRAVE DAUGHTERS' STRUGGLE WITH RARE SYNDROME
But despite everything she has been cheered by the generosity of people who have supported her Facebook appeal for Marfan Trust which supports the diagnosis and treatment of Marfan syndrome patients.
'It breaks my heart that others could go through what we have'
With a view to highlighting a severe cardiovascular manifestation in a patient with Marfan syndrome, as well as the underlying risk factors for such complications, we present the case of a 47-year-old patient addressed to our clinic with dyspnea and orthopnea, dizziness and fatigue, symptoms that had occurred for about 3 months and progressively worsened over the last week.
Can a leaky heart valve be solved?
The ocular features of Marfan syndrome results in decreased vision including bilateral ectopic lentis 80%, (subluxation is most frequently superotemporal), myopia and retinal detachment.
OCULAR PRESENTATION OF MARFAN SYNDROME--DIAGNOSIS AND MANAGEMENT
Marfan syndrome is a spectrum of heritable disorders of connective tissue with a high degree of clinical variability.
Gastrointestinal Symptoms in Marfan Syndrome and Hypermobile Ehlers-Danlos Syndrome
Genetic Testing Panel for Marfan Syndrome and Next-Generation Sequencing.
Identification of Novel Causal FBN1 Mutations in Pedigrees of Marfan Syndrome
There is no previous report in the literature about its association with Marfan syndrome. We describe here a case of a female with Marfan syndrome, who was diagnosed with symptomatic anomalous origin of the left coronary artery in the right Valsalva sinus.
Anomalous Coronary Artery Origin in a Young Patient with Marfan Syndrome
In summary we describe the case of a 43-year-old male with a novel pathogenic variant in FBN1 causing Marfan syndrome with the rare phenotype of bilateral popliteal aneurysms.
Patient with Marfan Syndrome and a Novel Variant in FBN1 Presenting with Bilateral Popliteal Artery Aneurysm
Marfan syndrome (MFS) is a connective tissue disorder comprising multiple organ manifestations caused by a mutation in the gene FBN1 that codes for the protein, fibrillin-1 [1].
Thoracoscopic Treatment of Pneumothorax in Marfan Syndrome: Hemostatic Patch to Support Lung Resection Recovery
Marfan syndrome (MFS) is an autosomal dominant inherited disease associated with systemic connective tissue disorders, particularly involving the ocular, cardiovascular, and skeletal systems.
Age Differences in Axial Length, Corneal Curvature, and Corneal Astigmatism in Marfan Syndrome with Ectopia Lentis

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