As part of the study, the team of researchers used a method called Mendelian
randomisation to explore this phenomenon further.
Using a new statistical technique called Mendelian
randomisation, they identified 96 gene mutations linked to BMI and body fat mass.
Enter Mendelian
randomisation. This is a relatively new type of "data science hack" being used to analyse health risks, said Karmel Choi, a postdoctoral research fellow in psychiatric genetics at Massachusetts General Hospital and the Harvard T.H.
Using a mendelian
randomisation study, the researchers looked at 67 798 men and women from England, Scotland and Wales with the UK Biobank cohort, for whom information on years of completed education and refractive error was available.
Using a technique called Mendelian
randomisation, they analysed 44 genetic variants associated with myopia and 69 genetic variants associated with years of schooling for 67,798 men and women aged 40 to 69 years.
A study of biomarker-driven therapy in metastatic colorectal cancer, or mCRC, sponsored by Hoffmann-La Roche (RHHBY) has been suspended "following iDMC review of cohort 4 data a temporary recruitment halt to the whole study and a temporary halt to
randomisation into cohort 4 has been undertaken," according to a post to ClinicalTrials.gov.
During the follow-up period after
randomisation, 15.2% in the chamomile group compared to 25.5% in the placebo group relapsed (non-significant).
M2 PHARMA-February 13, 2017-Parexel Launches ClinPhone
Randomisation and Trial Supply Management Mobile App
Second, the authors mentioned that "a total of 80 eligible subjects were recruited and randomised alternately into 2 groups"; such type of alternate allocation is not a true
randomisation procedure.
M2 EQUITYBITES-August 17, 2015-Neurocrine Biosciences completes subject
randomisation of phase III clinical trial of NBI-98854