clozapine


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clo·za·pine

(klō′zə-pēn′, -pĭn)
n.
An antipsychotic drug, C18H19ClN4, used as a sedative and in the treatment of schizophrenia.
[c(h)lo(ro)- + alteration of (dia)zepine, seven-member ring containing two nitrogens; see benzodiazepine.]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

clozapine

(ˈkləʊzəˌpiːn)
n
(Medicine) a sedative used to treat schizophrenia
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.clozapine - an antipsychotic drug (trade name Clozaril) used as a sedative and for treatment-resistant schizophrenia; know to have few side effects
Clozaril
antipsychotic, antipsychotic agent, antipsychotic drug, major tranquilizer, major tranquilliser, major tranquillizer, neuroleptic, neuroleptic agent, neuroleptic drug - tranquilizer used to treat psychotic conditions when a calming effect is desired
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
Translations

clozapine

n clozapina
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
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References in periodicals archive ?
Pimavanserin (Nuplazid), an atypical antipsychotic approved to treat hallucinations and delusions in Parkinson's disease, shows promise as a treatment for patients with refractory schizophrenia who fail to respond to clozapine, a retrospective study suggests.
Atypical used in Parkinson's lifts hallucinations, delusions
Our clinical team made a serendipitous discovery about the efficacy of pimavanserin in patients with schizophrenia who failed to respond to clozapine therapy
Pimavanserin: A potentially safer alternative to clozapine for refractory hallucinations and delusions
Cardiomyopathy and myocarditis are rarely seen but are potential mortal cardiotoxic effects of antipsychotic medication which are most commonly reported with clozapine treatment (9,10).
Olanzapine Associated Acute Peripheral Edema and Pericardial Effusion: A Case Report
He had been prescribed clozapine - anti-psychotic medication for schizophrenia - since 2013, which coroner for North Wales East and Central, John Gittins concluded had resulted in his death after toxic levels were found in his blood.
Toxic level of medicine killed man by accident
He had been prescribed clozapine - antipsychotic medication for schizophrenia - since 2013, which coroner for North Wales East and Central, John Gittins concluded had resulted in his death after toxic levels were found in his blood.
Toxic level of medicine killed man by accident
4, 2018 (HealthDay News) -- Remission can be achieved for most cases of schizophrenia and schizophreniform disorder with amisulpride and clozapine, according to a study published online Aug.
Remission of Schizophrenia Seen With Amisulpride, Clozapine; Symptomatic remission achieved for most with sequential administration of amisulpride, clozapine
Approved in 1989 for the treatment of resistent schizophrenia (2), clozapine is an antagonist of 5-HT2A, D1, D3 and a receptors and presents a relatively decrease potence as an antagonist of D2 receptors (3).
Buletin de Psihiatrie Integrative Clozapine treatment and risk of miocarditis in patients with refractory schizophrenia
Clozapine is a second-generation antipsychotic agent, which is considered to be more effective than other antipsychotics against treatment-resistant schizophrenia.
Clozapine-related Paroxysmal Supraventricular Tachycardia: a Case Report
Then, clozapine was started in a dose up to 425 mg daily leading to serum levels of 587 ng/mL (reference value: 50 to 700 ng/mL), with no clinical signs of response after 33 weeks.
Capgras syndrome in a first-episode, late-onset and super-refractory schizophrenia case
Clozapine is an atypical antipsychotic that is used to treat schizophrenia that is refractory to other psychiatric medications.
A Rare Presentation of Clozapine-Induced DRESS Syndrome
A 58-year-old female with hypertension, hyperlipidaemia, and type two diabetes presented with atypical central chest pain seven days after commencing clozapine for refractory schizophrenia.
Clozapine-Induced Myocarditis or Acute Coronary Syndrome? Optical Coherence Tomography to the Rescue

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